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Why Sleep Apnea Can Destroy Testosterone Levels

Jan 24, 2026 Iron Mountain Mens Health
Iron Mountain Mens Health

Many men come to Iron Mountain Men’s Health frustrated. They’re exhausted despite “sleeping” 7–8 hours. Their motivation is gone. Libido is low. Focus is poor. Strength and body composition are slipping.

Bloodwork often shows low or borderline testosterone.

What many of these men don’t realize is that the root cause may not start with their hormones at all — it may start with how they breathe at night.

Sleep apnea is one of the most underdiagnosed and overlooked causes of low testosterone in men.

What Is Sleep Apnea?

Sleep apnea is a condition where breathing repeatedly stops and starts during sleep. The most common form in men is obstructive sleep apnea (OSA), which occurs when the airway collapses or becomes blocked while sleeping.

Common risk factors include:

  • Excess body weight
  • Large neck circumference
  • Narrow airway anatomy
  • Alcohol use before bed
  • Sedatives or sleep medications

Many men have sleep apnea for years without knowing it.

Common Symptoms Men Ignore

  • Loud, chronic snoring
  • Waking up unrefreshed
  • Daytime fatigue or sleepiness
  • Morning headaches
  • Brain fog and poor concentration
  • Low libido or erectile dysfunction

Because these symptoms develop gradually, men often assume they’re just “getting older” or “burned out.”

How Testosterone Is Normally Produced During Sleep

Testosterone production is tightly linked to sleep quality, not just sleep duration.

Most testosterone is produced during:

  • Deep sleep
  • REM sleep
  • Uninterrupted sleep cycles

Healthy testosterone release depends on:

  • Consistent sleep architecture
  • Adequate oxygen levels
  • Low nighttime stress hormones

You can spend eight hours in bed and still sabotage testosterone production if your sleep is fragmented.

How Sleep Apnea Lowers Testosterone

Sleep apnea impacts testosterone through several powerful mechanisms.

1. Interrupted Deep Sleep

Men with sleep apnea experience dozens — sometimes hundreds — of micro-awakenings per night. These interruptions prevent the brain from sustaining deep and REM sleep, where testosterone production peaks.

The result: testosterone output drops, even if total sleep time looks “normal” on paper.

2. Repeated Oxygen Deprivation

During apnea episodes, oxygen levels fall repeatedly throughout the night. This chronic hypoxia directly impairs the function of Leydig cells, the cells in the testes responsible for testosterone production.

Over time, reduced oxygen = reduced testosterone.

3. Elevated Cortisol (Stress Hormone)

Sleep apnea places the body in a constant fight-or-flight state at night. This leads to chronically elevated cortisol, a hormone that directly suppresses testosterone production.

High cortisol and healthy testosterone do not coexist.

4. Metabolic Dysfunction and Fat Gain

Sleep apnea is strongly associated with:

  • Insulin resistance
  • Weight gain
  • Increased visceral fat

Body fat converts testosterone into estrogen through the aromatase enzyme. This means sleep apnea doesn’t just lower testosterone — it can actively shift hormonal balance in the wrong direction.

The Vicious Cycle: Low Testosterone Makes Sleep Apnea Worse

This relationship goes both ways.

Low testosterone contributes to:

  • Increased fat mass
  • Reduced muscle tone in the upper airway
  • Poor metabolic health

As testosterone declines, sleep apnea severity often worsens, creating a self-reinforcing downward spiral that many men get trapped in for years.

Why Treating Sleep Apnea Matters Before (or Alongside) TRT

Testosterone therapy cannot fully overcome the effects of untreated sleep apnea.

When sleep apnea is ignored:

  • TRT benefits may be blunted
  • Cardiovascular risk may increase
  • Hematocrit can rise more aggressively
  • Fatigue and brain fog may persist

At Iron Mountain Men’s Health, we focus on root causes, not just symptom suppression. Hormone optimization works best when sleep, breathing, and metabolic health are addressed together.

How Iron Mountain Men’s Health Approaches

This Issue We don’t believe in cookie-cutter TRT.

Our approach includes:

  • Evaluating symptoms, not just lab numbers
  • Interpreting testosterone in the context of sleep, stress, and metabolism
  • Screening for sleep-related issues when TRT results are suboptimal
  • Coordinating care when sleep evaluation is indicated

This comprehensive strategy leads to better outcomes and fewer complications.

Conclusion

Testosterone optimization doesn’t start with a syringe or a prescription. It starts with how well your body recovers at night.

Sleep apnea is one of the most powerful — and most ignored — drivers of hormonal decline in men. When identified and treated properly, it can unlock dramatic improvements in energy, mood, metabolism, and overall quality of life.

At Iron Mountain Men’s Health, our goal is simple:
help men feel strong, clear, and capable again — by addressing the real cause.

If you’re ready to take the next step, a comprehensive evaluation can make all the difference.

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Dr. Avidon Appel

About Author

Dr. Avidon Appel is the founder of Iron Mountain Men’s Health. He is an Internal Medicine Specialist based in Willow Grove, PA who specializes in men’s sexual health and hormone optimization and has over 19 years of experience in the medical field. He is a graduate of Philadelphia College of Osteopathic Medicine, as well as Saint Joseph’s University.