How to Manage Polycythemia Caused by Testosterone Replacement Therapy
This article will discuss the possible risks of polycythemia caused by testosterone replacement therapy, and how to manage it. Read on to learn more about the condition, its symptoms, and its connection to testosterone replacement therapy.
What is Polycythemia?
Polycythemia is a medical condition in which there is an increase in the number of red blood cells in your blood. This may cause the blood to be thicker than normal. Polycythemia can lead to health problems such as an increased risk of heart attack or stroke.
Causes of Polycythemia
Polycythemia may be caused by a variety of factors, including:
Testosterone replacement therapy
Genetic disorders
Smoking
Obesity
Chronic diseases such as heart or kidney disease
Cancer
Radiation therapy
Certain medications, such as chemotherapy drugs
Steroid use
Symptoms of Polycythemia
Symptoms of polycythemia can include the following:
Headache
Dizziness
Neck pain
Chest pain
Shortness of breath
Weakness
Fatigue
Prolonged bleeding time
Swelling of the hands and feet
Reddish-brown urine
If you are experiencing any of these symptoms, it is important to see your doctor right away. Left untreated, polycythemia can lead to serious health problems.
Managing Polycythemia
If you are diagnosed with polycythemia, your doctor will likely recommend treatment to manage the condition. Treatments may include:
Taking blood-thinning medications such as aspirin or warfarin (Coumadin)
Restricting your activity level
Receiving a phlebotomy, which is a procedure that removes blood from your body
Taking medications to lower your red blood cell count, such as hydroxyurea (Droxia, Hydrea) or anagrelide (Agrylin)
Receiving radiation therapy on your head and neck
Undergoing a bone marrow transplant
Having surgery to remove your spleen
Taking testosterone replacement therapy (TRT).
If you are taking TRT and are diagnosed with polycythemia, your doctor may recommend stopping TRT and/or exploring any of the aforementioned treatment options. Managing polycythemia can be a challenge, but with proper treatment you can live a healthy life. Talk to your doctor if you have any questions or concerns.
Polycythemia Prevention
There are a few ways to help prevent polycythemia from developing while on testosterone replacement therapy:
Maintain a Healthy Weight – being overweight can increase the risk of polycythemia
Drink Plenty of Fluids – staying hydrated will prevent the build-up of red blood cells
Get Regular Exercise – exercise keeps the body healthy and can lower your risk of experiencing polycythemia
Avoid Tobacco Smoke – smoking increases the risk of polycythemia
Follow Your Doctor’s Instructions – listen to your doctor’s recommendations and follow their instructions closely
Conclusion
Polycythemia can be a serious medical condition, but it can be managed with proper treatment. If you are taking testosterone replacement therapy and are diagnosed with polycythemia, your doctor may recommend stopping TRT and/or exploring some of the treatment options listed above. If you find that you're experiencing any of the symptoms of polycythemia while taking TRT, visit a doctor as soon as possible.
March 8, 2022
Written By
Dr. Avidon Appel
Fact-checked By
Dr. Avidon Appel
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