How Long Does Ozempic Fatigue Last?

June 26, 2024
Fact-checked by Dr. Avidon Appel

Ozempic has garnered attention not just for its efficacy, but also for its side effects. Among these, fatigue is a commonly reported issue, and prospective users often wonder just how long this tiredness will last. In this article, we'll delve into the specifics of Ozempic fatigue, shed light on what you can expect, and offer practical tips to help you cope.

Does Ozempic Make You Tired?

Fatigue is indeed one of the side effects of Ozempic for weight loss. However, less than five percent of users report it.

Why Does Ozempic Make You Tired?

There are a few reasons why Ozempic can cause tiredness, including:

  • Low Blood Sugar: Ozempic affects blood sugar levels, and low blood sugar (hypoglycemia) can cause fatigue.

  • Changes in Eating Habits: Users generally experience a drop in appetite while taking Ozempic, and less food intake can lead to a decrease in energy levels.

  • Digestive Issues: Ozempic can cause digestive side effects such as nausea, diarrhea, and constipation. These symptoms can cause dehydration, which can lead to fatigue.

Does Ozempic Fatigue Go Away?

For most patients, Ozempic fatigue subsides as the body adjusts to the medication.

So How Long Does Ozempic Fatigue Last?

The duration of Ozempic fatigue can vary from user to user. That said, patients usually experience this side effect when they first start the medication, and it tends to subside within a few weeks.

If your Ozempic fatigue persists for longer or becomes particularly bothersome, it's important to consult a doctor.

How Can You Combat Ozempic Fatigue?

Ozempic fatigue can be vexing, but there are several strategies you can implement to alleviate it, such as:

  • Eat a Balanced Diet: Eating a nutritious diet rich in fruits, vegetables, lean proteins, and whole grains can give your body the essential nutrients it needs for energy.

  • Stay Hydrated: Dehydration can exacerbate feelings of tiredness, so be sure to drink plenty of water throughout the day.

  • Exercise: Engaging in regular physical activity can boost your overall energy levels and improve your mood.

  • Get Adequate Sleep: Aim for seven to nine hours of quality sleep each night to allow your body to recharge.

  • Monitor Your Blood Sugar Levels: Keeping your blood sugar levels stable can help reduce energy dips throughout the day.

What Are Some Other Side Effects of Ozempic?

Some of the other side effects that Ozempic for weight loss can cause include:

  • Abdominal pain

  • Constipation

  • Diarrhea

  • Dizziness

  • Fatigue

  • Headache

  • Heartburn

  • Loss of appetite

  • Nausea

  • Vomiting

Does Ozempic Cause Brain Fog?

While some Ozempic users report cognitive side effects like difficulty concentrating and memory lapses, clinical evidence linking Ozempic to brain fog is limited. The aforementioned cognitive issues can stem from a number of causes, including changes in blood sugar levels, lifestyle adjustments, and individual health conditions.

How Long Does it Take for Your Body to Adjust to Ozempic?

The body typically needs time to adjust to Ozempic for weight loss. Generally, it takes several weeks for it to fully acclimate. During this period, you may experience side effects like nausea, diarrhea, and/or constipation.

For that reason, it's important to follow your doctor's instructions and refrain from adjusting your dose without their permission.


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June 26, 2024

Written By
Dr. Avidon Appel

Fact-checked By
Dr. Avidon Appel

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About Author

Dr. Avidon Appel is the founder of Iron Mountain Men’s Health. He is an Internal Medicine Specialist based in Willow Grove, PA who specializes in men’s sexual health and hormone optimization and has over 19 years of experience in the medical field. He is a graduate of Philadelphia College of Osteopathic Medicine, as well as Saint Joseph’s University.

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