Does Ozempic Make You Tired?

January 9, 2024
Fact-checked by Dr. Avidon Appel

Ozempic, a medication well known for its effectiveness in facilitating weight loss, has gained notoriety in the medical world. However, like all medications, it comes with its share of potential side effects. One concern that commonly surfaces is whether Ozempic induces fatigue in those who use it. In this blog, we will explore why you may experience fatigue while taking Ozempic and what you can do about it.

What Are the Most Common Side Effects of Ozempic?

Ozempic carries several common side effects. Such effects include nausea, vomiting, diarrhea, abdominal pain, and fatigue. These are typically mild and tend to diminish over time as the body adjusts to the medication.

It's important to note that everybody reacts differently to medications, and while these are the most common side effects, not everyone taking Ozempic will experience them. Always consult your healthcare provider for personalized advice.

Why Is Ozempic Making Me So Tired?

Ozempic can cause feelings of tiredness in some individuals. This effect can be attributed to a variety of factors. Firstly, the medication works by regulating blood glucose levels, and any fluctuation in these levels can lead to fatigue.

Secondly, common side effects of Ozempic include gastrointestinal disturbances like nausea, vomiting, or diarrhea, which can indirectly contribute to feelings of tiredness by depleting the body's hydration and nutrient levels. Lastly, it's worth noting that individual reactions to medication can vary significantly, with some individuals more susceptible to certain side effects than others.

Ways to Combat Ozempic Fatigue

Exercise Regularly

Exercise is one of the most effective ways to combat Ozempic-induced fatigue. Regular physical activity boosts energy levels and improves blood flow, helping to counteract feelings of tiredness and lethargy. Aim for at least 30 minutes of moderate exercise daily, such as brisk walking, cycling, or swimming.

Eat Balanced Diet

Maintaining a balanced diet is crucial to managing Ozempic fatigue. Consuming nutrient-rich foods can provide the energy you need to get through the day. Include whole grains, lean proteins, fruits, vegetables, and healthy fats in your diet. Avoid processed foods and sugary drinks that can cause energy crashes.

Stay Hydrated

Dehydration can exacerbate feelings of fatigue. Ensure to drink enough fluids throughout the day, prioritizing water over sugary or caffeinated beverages.

Get Enough Sleep

Getting enough sleep is key in managing fatigue. Aim for seven to nine hours of quality sleep each night. If you're having trouble sleeping, try creating a bedtime routine to help your body know it's time to rest.

Consult Your Doctor

If fatigue persists despite these measures, it's important to consult your doctor. They can determine if dosage adjustments or alternative medications are necessary.

How Long Does it Take for Your Body to Get Used to Ozempic?

Adjusting to Ozempic works differently for each individual, but on average it takes four to five weeks for your body to become accustomed to the medication. Starting with a low dose and gradually increasing it over time can help mitigate side effects and ease your body into tolerance of the medication.

This slow buildup allows your body to adjust to the new drug and can reduce the intensity of side effects such as fatigue. Remember to contact your doctor if you experience any severe side effects during this adjustment period, or if you find your body isn't adjusting to Ozempic as it should be.


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January 9, 2024

Written By
Dr. Avidon Appel

Fact-checked By
Dr. Avidon Appel

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About Author

Dr. Avidon Appel is the founder of Iron Mountain Men’s Health. He is an Internal Medicine Specialist based in Willow Grove, PA who specializes in men’s sexual health and hormone optimization and has over 19 years of experience in the medical field. He is a graduate of Philadelphia College of Osteopathic Medicine, as well as Saint Joseph’s University.

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